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These characteristics are similar to those reported for GABAergic Gipr KO mice, which also had attenuated weight gain on HFD exposure, with reduced fat and lean mass 5,11
Hepatocyte Growth Factor (HGF) is a pleotropic cytokine that activates the c-Met tyrosine kinase receptor
Primard C, Monchtre-Leroy E, Del Campo J, Valsesia S, Nikly E, Chevandier M, et al
While this idea shows a more complex picture from the popular one where free radicals and oxidants are bad and antioxidants are good, it implies that GSH is an essential molecule not only in acting as an antioxidant but also in the absence of oxidative stress, as an endogenous signaling molecule
10.1001/jamanetworkopen.2023.42210 [DOI] [PMC free article] [PubMed] [Google Scholar] Cubanski, J., Neuman, T., & Damico, A