Cytoreductive removal is also indicated whenever tumour bulk or symptoms threaten organ function
Despite the evidence of efficacy in the relief of symptoms, as well as an association with diminished WHF and all-cause mortality risk [31] the neutral mortality findings in RELAX-AHF-2 resulted in a lack of approval of serelaxin (Reasanz , Novartis Europharm Ltd, Sussex, UK) use in the AHF treatment [48]
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