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And GLP-1s do come with side effects that for some patients have been serious enough to lead to discontinuation

Access can be a big problem for lower-income people, and due to the popularity of the drugs, there have been shortages and restrictions

In this 72-week study of 2,539 adults [1] with obesity, participants receiving 15mg weekly tirzepatide achieved an average weight reduction of 22.5% compared to 2.4% with placebo

doi: 10.1016/S0198-8859(99)00144-5