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Important : Patients on GLP-1 medications must usually pause treatment for several weeks before surgery

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(Standard titration begins at a low weekly dose and increases gradually to enhance tolerability

Do not drink if you're fasting or have eaten very little that day, if you're experiencing active gastrointestinal side effects from semaglutide, or if you take other medications that interact with alcohol (such as certain diabetes drugs, blood pressure medications, or psychiatric medications)

Zepbound, with its dual-agonist approach, has showcased a promising edge in efficacy, potentially driving a paradigm shift in obesity treatment, while Wegovy, though slightly trailing, remains a solid contender, especially with potential future combinations enhancing its performance

However, as discussed next, a bona fide indication for GLP-1 RAs to reduce the risk of developing HF or to treat chronic HF arguably requires the resolution of several unknowns