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SURMOUNT-5 was a 72-week, multi-centre, randomised, open-label, Phase 3b trial evaluating the efficacy and safety of tirzepatide compared with semaglutide in adults with obesity, or overweight with at least one of the following comorbidities: hypertension, dyslipidaemia, obstructive sleep apnoea (OSA) or cardiovascular disease, who did not have diabetes

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TMJ dysfunction impacts the temporomandibular joint (the hinge that connects your lower jaw to the skull), which is essential for chewing, speaking, and facial expressions

In contrast, compounded tirzepatide in the U.S

Repeated injections in one area increase inflammation, bruising, and discomfort

Working alongside medical professionals can help keep health at the center of the process while providing structure and accountability