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In the TRIUMPH-1 trial, participants were given either 4 mg, 9 mg, or 12 mg of retatrutide

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Low levels of serum GLP-1 were reported in 260 patients with a diagnosis of first-episode psychosis compared with healthy controls 130

Heres the punchline: the study does not show protection of lean mass

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Significant weight loss from any cause, including diet, surgery, or any GLP-1 medication, can trigger temporary hair shedding (telogen effluvium) because of how the body responds to rapid change