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[DOI] [Google Scholar] 41.Lee M.K., Yeo H., Kim J., Kim Y.C

In some embodiments, the otic formulation or composition comprises about 11% by weight of the therapeutic agent, or pharmaceutically acceptable prodrug or salt thereof

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LKB1 phosphorylates and activates AMP-activated protein kinase (AMPK), which functions as an energetic sensor, regulating glucose and lipid metabolism in response to alterations in nutrients and intracellular energy levels [7]