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CIBER is an initiative of Instituto de Salud Carlos III (Ministerio de Sanidad, Spain)

The GLP-1 agonist Ex-4 dramatically reduced the ROS level in PA treated hepatic cells, whereas insulin increased the basal ROS level

Interestingly, astrocyte reactivity is influenced and modulated by microglia activation, suggesting that drugs targeting microglia may offer an indirect strategy to combat reactive astrocytes

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