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Indeed, previous studies indicate that Nfe2l2 , along with NRF2 target genes such as Gclc and Gclm , exhibits circadian oscillations in the lung, as well as kidney, and aorta (58, 59)

However, in cells lacking IR, IGF-1 further increased BrdU incorporation, whereas the effect of insulin was diminished as expected

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Underreporting of Gastrointestinal Symptoms : In clinical trials, some gastrointestinal symptoms, including those related to acid reflux, might be underreported

PLoS Biol 2018;16, e2004663, doi:10.1371/journal.pbio.2004663

(2005) Cognitive functioning and wellbeing in euthyroid patients on thyroxine replacement therapy for primary hypothyroidism