Choosing between the two depends on individual goals, treatment areas, and tolerance for side effects
Controlled drug delivery with nanoassemblies of redox-responsive prodrug and polyprodrug amphiphiles
In these populations, restoring glutathione levels can improve hepatic function, reduce systemic inflammation, and support mitochondrial ATP production
Standard protocols start at 0.25mg weekly for the first four weeks, titrating up to 0.5mg, then 1.0mg, and potentially 1.7mg or 2.4mg depending on response and tolerance
This class of medications (commonly-branded as Ozempic, Wegovy, Trulicity, Mounjaro, and more), which were initially developed to treat Type 2 diabetes, have become the weight loss method in the last half-decade, with more Americans seeking them out as a new way to lose weight, if they can access them
In the context of FXS, instead of targeting NATs of the FMR1 gene, there has been success in restoring FMR1 expression in induced pluripotent stem cells (iPSCs) through direct CRISPR-Cas9-mediated deletion of pathological repeat sequences of the sense gene [61]