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In individuals with gastroparesis, stomach muscle contractions become weak and may stop moving forward through the gastrointestinal tract entirely

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At least 70 enzymes have been identified as requiring CoA or ACP derivatives for their function including the same critical thiamine-dependent enzymes described above, the pyruvate dehydrogenase complex (PDHc), 2-oxoglutarate (-ketoglutarate) dehydrogenase complex (OGDH), and branched-chain -ketoacid dehydrogenase complex (BCKD)

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California, New Jersey, New York, Washington, Massachusetts, Connecticut, Oregon, Colorado, and others have state-level laws with their own thresholds, durations, and coverage rules

Lower BMI thresholds may apply for certain ethnic groups