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268,269 Classical LNPs typically include ionizable lipids (ILs) or cationic lipids (CLs), auxiliary lipids, cholesterol, and Polyethylene glycol (PEGylated) lipids (Fig

High-dose therapy may also cause a brief increase in blood pressure, though this usually returns to baseline within a few hours

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In fact, its role as a co-substrate for the selenium-dependent GPX has been recognized as the most important mechanism for reduction of H 2 O 2 and lipid hydroperoxides