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Indeed the activation of prodrugs in GST overexpressing cells may lead to high concentrations of an active drug, as compared to normal cells with moderate enzyme levels
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Biological and Mechanistic Characterization of Novel Prodrugs of Green Tea Polyphenol Epigallocatechin Gallate Analogs in Human Leiomyoma Cell Lines
10.1111/j.1460-9568.2006.04692.x 58 KawaguchiY.KubotaY
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The researchers next applied glutathione, an antioxidant that is normally found in our cells, directly on the skull surface after a brain injury
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