As examples, some of these predictions are stated here: Under conditions of B12 insufficiency, excess folic acid intake will cause the following: Diversion of holoTC from serum to hemopoietic cells to support reticulocyte proliferation Loss of holoTC in urine due to interference of its reuptake by the megalin-receptor complex in the renal tubules Reduced availability of holoTC to the liver, brain, and other tissues due to its diversion to the hemopoietic system and loss in the urine
Without enough B12, you might face anemia, nerve issues, and heart disease risks
A number of researchers have called for the replacement of cyanocobalamin in supplements with other, safer forms of vitamin B12 listed above
Short-term folic acid supplementation induces variable and paradoxical changes in plasma homocyst(e)ine concentrations
Vitamin B12 deficiency can potentially cause severe and irreversible damage, especially to the brain and nervous system
At this point the count will hit the lowest level (also called the nadir) and physicians will want to make sure that it is not too low
