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15 16 Sermorelin, under the brand name Geref, was FDA-approved for pediatric growth hormone deficiency but was later taken off the market for non-medical reasons

[DOI] [PMC free article] [PubMed] [Google Scholar] 64.Dong H, Xia Y, Jin S, Xue C, Wang Y, Hu R, et al

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The success of such surface-based conjugation hinges on two critical criteria: (i) the availability of orthogonal chemical handles that selectively target specific amino acid residues without cross-reacting with other surface-exposed side chains, and (ii) coupling chemistries that preserve native protein folding and function

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