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In contrast, when Dusp4 is methylated normally, its expression decreases, and phosphorylated ERK remains active longer to induce ptgs2 expression, which subsequently activates the PGE2-TGF1 signaling pathway to promote tissue repair

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These nine essential amino acids are histidine, isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan, and valine

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