As part of this response, ANP stimulates lipolysis in adipocytes through the natriuretic peptide receptor-A (NPR-A) (109) and cyclic GMP (cGMP)/Protein kinase G (PKG) pathway to phosphorylate HSL and PLIN1 (110) (Figure 2)
10.1016/B978-012543590-1/50021-4 Antioxidant food supplements in human health
This is what causes the "haggard" or "deflated" look
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Cell Metab 5:253264 MacMullen C, Fang J, Hsu BY et al (2001) Hyperinsulinism/hyperammonemia syndrome in children with regulatory mutations in the inhibitory guanosine triphosphate-binding domain of glutamate dehydrogenase
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