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Indeed, transgenic mice given the human presenilin-1 (PS1) genewhich encodes one of the two subunits of -secretasewith one missense mutation (Val97Leu, PS1V97L) formed abundant A oligomers (Zhang et al., 2014), produced cognitive deficits, and exhibited cellular oxidative stress markers (Tian et al., 2019
Neurochemical Journal
Adjunct N-acetylcysteine treatment in hospitalized patients with HIV-associated tuberculosis dampens the oxidative stress in peripheral blood: results from the RIPENACTB study trial
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Proc Natl Acad Sci U S A 101:37805, PMID: 15004285 Townsend DM, Manevich Y, He L, Hutchens S, Pazoles CJ, Tew KD (2009) Novel role for glutathione S -transferase pi Regulator of protein S-glutathionylation following oxidative and nitrosative stress
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