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Dietary modifications support tolerance: increase soluble fiber gradually, stay well hydrated (at least 23 liters daily), limit high-fat foods that accelerate transit, and eat smaller, more frequent meals

Supplementation at 5001,000mg daily reverses fatty liver in deficient individuals within 812 weeks

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Available from: MARCH Trial Team

Melanoma antigen-like gene 2 ( MAGEL2 ) Mutation of MAGEL2 leads to the development of Prader-Willi Syndrome (PWS), a genetic disease that causes obesity and mental retardation [162]

Each substance was reviewed against a specific nominated indication, not against general use