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Similarly, trials of semaglutide have shown substantial reductions in waist circumferencea clinical surrogate for visceral adiposityalongside improvements in cardiometabolic markers including hemoglobin A1c, blood pressure, and lipid profiles

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While normal menstrual cycle levels of estradiol promote the healthy development and receptivity of the endometrium, the high estradiol levels of endometriosis patients elicit pathologic changes in the eutopic proliferative and secretory endometrium

That figure increased to 24.2% at 48 weeks

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