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Observational studies investigating the relationship between anesthesia and dementia have had mixed results, but some studies have shown increased cytotoxicity and build up of amyloid plaque following general anesthesia (2)

Cell Regen

Duan S, Cao Y, Chen P, Yang Y, Zhang Y

The mechanisms sustaining this heterogeneity are unknown, although it should be acknowledged that CVOTs lack the statistical power to reliably detect differences in specific MACE components

OS arises when an imbalance between free-radical formation and antioxidant defenses occurs, that is, when ROS concentration overwhelms the antioxidant capacity within the RBC [19]

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