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Human clinical trials have not been completed

While there are numerous claims about the benefits of such supplements, it is essential to remember that the United States Food and Drug Administration (FDA) do not require most supplements to prove their effectiveness in clinical studies

Because those signals converge on appetite from different directions, the hypothesis is greater total reduction in energy intake than either alone

Finally, individual patient data are lacking

If a patient is interested in starting a GLP-1, health care professionals should follow the patients lead, ask them what they know about the medication and provide evidence-based information on the therapy, Ihlenfeld said