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DON impacts the mucus layer composition by downregulating the expression of the gene coding for MUC2, as shown in a trial with human goblet cells (Pinton et al., 2015)
Depending on the capacity of the cellular GSH buffer, either a signal is perceived and relayed, resulting in signaling cascades that elicit downstream responses, or signals may be attenuated and even stop [144]
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Due to its structure, skin lipids can be packed tightly and in turn, this strengthens the barrier and reduces water loss
L-
Mitochondria is one of the important cellular organelles which GSH involved in its function, whereby, it plays a key role in regulating apoptosis versus necrosis
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