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The drug mimics the GLP-1 hormone, released after a meal, which helps curb appetite and slows foods passage through the stomach

The oral formulation appears to be bringing new patients into treatment rather than simply shifting share among existing users

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Effects of GLP-1 agonists on vascular endothelium Enhancing endothelial function A review of the literature revealed multiple preclinical studies on GLP-1R agonists in animal models demonstrating the molecular mechanisms behind their pharmacological effects

None of these peptides are licensed medicines in the UK

Retatrutide : Not yet submitted for regulatory approval