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doi: 10.1136/bcr.02.2011.3854

Structure-activity relationship work has produced a series of analogues built around the ipamorelin scaffold

Slower dose escalation

Nat Neurosci 2011

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The underlying antihangover mechanisms include reducing the intestinal absorption of ethanol or its metabolites, increasing the activity of ethanol metabolizing enzymes, development of fatty acid oxidation in mitochondria, inhibition of inflammatory response, blocking the target receptors of ethanol in the body, and possession of antioxidant activity under the oxidative stress developed by ethanol consumption