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Statistics show that 35% of the UK population struggles with joint problems, with one in five individuals affected to varying degrees.Milder cases include conditions such as arthritis, rheumatism, and gout, with symptoms like pain, stiffness, swelling, fatigue, and reduced mobility

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While synthetic nanocarriers including cationic liposomes and polymeric nanoparticles have been used for the delivery of DNA vaccines across cell membranes, targeted formulations could further enhance nuclear translocation of the plasmid DNA 47

Resnik SR, Geisler EL, Reyes N, Lozano J, Ramirez-Caussade R, Resnik BI

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