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12 Abnormally high levels of the neurofilament light chain protein in blood, a biomarker of damaged neurons, were found to start an average of 22 years before the median estimated age of symptom onset

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42 , hinting at possible anti-cancer effects under some conditions

Amide hydrolysis is illustrated in the following example: Note Hydrolysis of an amide in acid solution actually gives a carboxylic acid and the salt of ammonia or an amine (the ammonia or amine initially formed is neutralized by the acid)

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