PRE measurements were made using 15 N-labeled Cys1253Ala and Cys1253Ala/Thr1273Glu mutants of the S tail peptide that were reacted with 10 molar equivalents of MTSL (Santa Cruz Biotechnology, USA) for 1-2 hours at room temperature
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Marzatico F, et al
The present review highlights the recent advances in the preclinical development and clinical applications of RNA-based therapeutics, focusing on the delivery strategies, biological targets, and pharmacological optimisation, together with key clinical data
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