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In addition to the examples listed in the last section, embryonic deletion of Dnmt3a results in neuronal dysfunction, such as hypoactivity, motor abnormalities, decreased neuromuscular function, fewer motor neurons, and a shortened lifespan [73]

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(46) comparing T1D patients, who received combined kidney and pancreas transplantation, one group received a pancreatic graft allowing portal delivery of insulin, while the other, a graft with systemic pancreas drainage

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