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Donors with infections caused by hepatitis B virus, hepatitis C virus, human immunodeficiency virus, syphilis, cytomegalovirus, EpsteinBarr virus, or human T-lymphotropic virus were excluded from the final donor pool

J.JdarE.et al (2019)

ChemElectroChem 12 , e202500142 (2025)

Characterization of the biophysical properties of the mutated channels and their response to sympathetic activity has helped to identify the importance of EADs and sympathetic stimulation as proarrhythmic triggers, providing the scientific basis for beta-blocker therapy (or left cardiac sympathetic denervation) as a mainstay of antiarrhythmic therapy in LQTS [29]

Furthermore, obesity and T2DM lead to systemic inflammation, increasing pro-inflammatory brain cytokines, which may, in turn, interfere with insulin signaling and neurotransmission [92]

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