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The combination of DNase-I + amikacin resulted in a strong increase in dead biofilm compared to DNase I treatment alone, and the triple therapy combination of GSH + DNase-I + amikacin showed the highest level of biofilm disruption (Figure 3C)

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Based on the assumption of an average haematocrit of 45%, 100 l whole blood contains ~55l plasma, which is ~18-fold less than the 1 ml for which the cartridge is approved

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