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These uncommon reactions may indicate improper injection technique or a site-specific sensitivity that can be addressed through coaching or alternative approaches

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However, in states of leptin resistance such as obesity, this regulatory mechanism may be impaired (102, 103)

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*Correspondence: Jeroen Degroote [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Hazard sued the state, claiming it was being discriminated against by not qualifying to enact the tax