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The onset, duration, and severity of neonatal opioid withdrawal syndrome vary based on the specific opioid used, duration of use, timing and amount of last maternal use, and rate of elimination of the drug by the newborn

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GHK-Cu is a naturally occurring copper-binding peptide first identified in human plasma

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The findings stimulate further studies in large biobank samples to clarify whether such signatures could prove valuable for detecting pathology or follow-up of treatment effect in clinical trials