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The transformation of the catechol group into o-quinones is a chemical reaction involving the oxidation of the hydroxyl group at the ortho position of the phenolic ring [163]

Similar negative results were also verified in other studies (Di Lullo et al., 2015

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In the context of lipid metabolism, targeting pathways such as ether lipid synthesis, fatty acid synthase (FASN), or the ACLY/ACC axis has been shown to induce mitochondrial stress and ROS accumulation, thereby enhancing apoptotic responses [144]

Int J Endocrinol 2017:1835195