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HSPA2 HSPA2, previously considered a relatively minor member of the HSP70 family, is now recognized as playing key roles in cell growth and mitosis within epithelial tissues, as well as participating in extracellular signaling (Sojka et al., 2023)
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Medications that stimulate the CYP system can predispose patients to APAP hepatotoxicity by causing enhanced production of NAPQI via the oxidative pathway.25 Case series reports have concluded that in 50% of adult patients with APAP-induced acute liver failure, the life-threatening condition was preceded by ingestion of potentially hepatotoxic herbs within 8 weeks of hospital presentation.4 The prescription agents known for their hepatotoxic tendencies include anti-epileptic drugs, such as phenobarbital, phenytoin and carbamazepine, as well as anti-tuberculosis drugs, such as isoniazid and rifampin
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