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Before pursuing B12 injections or other interventions marketed for weight loss, patients should consult their GP for proper assessment, investigation of any underlying medical conditions affecting weight, and discussion of evidence-based treatment options

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The plSAM plasmid contains a core component named SAM, which consists of the signal peptide (SPusp45), the propeptide (PS), the multiple clone site (MCS), a designed M cell-targeting peptide (Mtp), and the peptidoglycan-binding domain of AcmA (cA domain)

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