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The prescribing information states that Mounjaro is contraindicated in patients with a personal or family history of medullary thyroid carcinoma, or MTC, or Multiple Endocrine Neoplasia syndrome type 2

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Chang and colleagues showed in 2011 that the peptide upregulates growth-hormone receptor expression on tendon fibroblasts and increases their migration and survival in culture, an effect that has been reproduced across several Achilles- and quadriceps-tendon transection models in rats