Liraglutide 3 mg (Saxenda) a once-daily GLP-1 receptor agonist licensed for obesity management (NICE TA664)
Seminal preclinical studies beginning in 2002 first illustrated the neurotrophic and neuroprotective capacity of GLP-1R agonistsGLP-1 and structurally related GLP-1R agonist exendin-4 were found to enhance neurite outgrowth, promote nerve growth factor (NGF)-mediated neuronal differentiation, protect against apoptosis, and maintain cholinergic neuronal health and function in cultured neurons and rodent models of neurodegeneration [27,28,29]
Prescribing Information: Qsymia (phentermine/topiramate ER) capsules
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Medications most commonly affected include oral contraceptives, thyroid medications (levothyroxine), blood pressure medications, and some psychiatric medications
Vitamin B6 (as Pyridoxal 5-Phosphate), Vitamin B12 (as Methylocobalamin), Actiponin Gynostemma Pentaphyllum extract (leaf), Green tea extract (leaf), Other Ingredients: Floli50 (Organic Brown Rice Grain Flower, Organic Brown Rice Sprouted Protein), Hypromellose Vegan Capsule