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Similarly, in the combined case-control and cohort study by Wium-Andersen and colleagues, 33 low doses of metformin, DPP-4 inhibitors, GLP-1 analogs, and SGLT2 inhibitors were associated with a lower risk of depression in patients with diabetes compared to non users, with the lowest risk for sodium-glucose transport protein 2 inhibitor users

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Collectively, the existing preclinical and clinical data suggest that GLP-1 is involved in the pathogenesis of alcohol dependence disorders, and GLP-1R is a promising target for the development of appropriate drugs [88]

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