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49 In another phase 1 study conducted in 37 Japanese patients, the most common treatment-related side effects were nausea, vomiting, abdominal discomfort, diarrhea, and headache, mostly mild to moderate in severity

This includes initial evaluations, follow-ups, and ongoing care management

They were all large-scale trials involving 3,000 to 18,000 patients who were either at high risk of or having established ASCVD, with trial durations ranging from 15 to 60 months

doi: 10.1016/j.cmi.2016.04.024 93 ArifuzzamanMWonTHLiTTYanoHDigumarthiSHerasAFet al

Kaufman said he didnt want to sound hyperbolic about the new drugs, but then sounded pretty hyperbolic when he described his short, but so far positive, experience with them in these diseases as eye-opening and incredible

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