They are looking at potential side effects, how the body responds over time, and whether any rare side effects might show up in larger groups of people
Can Employers Test for Semaglutide
Then theres tirzepatide, used in Mounjaro
In terms of safety, TRT has its own considerations (polycythemia, prostate effects, etc.) which are unrelated to PT-141s profile
Novo Nordisk has published phase 3 data showing that a dual therapy comprising cagrilintide and semaglutide (the GLP-1 agonist in Wegovy), coupled with lifestyle interventions, achieved an average of 13.7% weight loss in patients with type 2 diabetes, who are also overweight or obese, over a period of 68 weeks 8
Oral semaglutide for weight loss in non-diabetics is approved, so a diabetes diagnosis isn't necessary