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Conclusively, research on GLP-1R and its agonists marks a promising direction in metabolic disease therapy, extending their potential beyond glucose regulation and offering hope for more comprehensive approaches in addressing metabolic diseases

The medication should be taken with food to reduce nausea and improve tolerability

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Other supportive lifestyle interventions Other lifestyle interventions are essential to support individuals using GLP-1s as part of the recommended multicomponent lifestyle programs that are the foundation of obesity treatment [88,171,172]