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it facilitates weight loss primarily through appetite suppression and reduced caloric intake rather than increasing basal metabolic rate

doi: 10.1038/s41591-025-04106-7

Brand name versions of both semaglutide and tirzepatide are FDA approved for weight loss in adults with a body mass index (BMI) of 30 or greater (or 27 or greater with at least one weight-related comorbidity)

Understanding Semaglutide and Menopause-Related Weight Gain Erica*, 48, from South Jersey, says no amount of calorie-cutting, hot yoga, or Pilates could budge the 12 pounds she acquired during perimenopause, much of it around the waistline

And their lives