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GLP-1 agonists commonly cause mild gastrointestinal effects like nausea or reduced appetite, which often subside within weeks

By stimulating the pituitary rather than flooding the bloodstream with hormone, this approach is designed to preserve that pulsatile pattern

Sand TE, Jacobsen S

Availability of data and materials All relevant data are provided in the manuscript

In the maintenance phase, the frequency is typically reduced significantly

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