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A holistic approach to obesity management incorporating behavioural support alongside pharmacotherapy is generally recommended in line with NICE guidance on weight management interventions
However, when using semaglutide for weight loss, some people may experience a reduction in overall body weight, which can include a combination of fat and muscle loss
Understanding why it happens and what you can do about it is the first step toward regaining confidence and control
Medication combinations require special attention
The existing pattern across the GLP-1 class is that the weight-loss curve is driven hardest during titration and the first several months at target dose, and that once the primary loss is achieved, maintenance becomes a separate problem with a different tolerability budget
Phentermine is a Schedule IV controlled substance, which means it has some potential for abuse and dependence
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