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Surprisingly, it is commonly seen in individuals who do not play golf

The N-terminal finger (residues 17) of one protomer inserts itself between domains II and III of its neighbouring protomer, and promotes the formation of the dimer and the S1 subsite in the neighbouring protomer 83

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For example, a ferroptosis-prone chondrocyte cluster with high expression of ACSL4 and Tf, but low expression of FTH1 and TRPV1, has been identified in severely degenerated cartilage regions (42)