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To estimate the combined uncertainty in outcomes, we performed probabilistic sensitivity analyses using 1000 Monte Carlo simulations based on the uncertainty in the model variables, drawing model variables randomly from the distributions in Table 1

For many, the issue is not a lack of effort but rather how the body regulates hunger, metabolism, and fat storage

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ABSTRACT INTRODUCTION GLUCAGON GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE GLUCAGON-LIKE PEPTIDE-1 DUAL GLUCAGON/GLUCAGON-LIKE PEPTIDE-1 RECEPTOR CO-AGONISTS DUAL GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE/GLUCAGON-LIKE PEPTIDE-1 RECEPTOR CO-AGONISTS TRIPLE GLUCAGON-LIKE PEPTIDE-1/GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE/GLUCAGON RECEPTOR TRIAGONISTS CONCLUSIONS Article information References ABSTRACT Obesity is the fifth leading risk factor for global deaths with numbers continuing to increase worldwide