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Mechanistically, Desulfovibrio desulfuricans compromises intestinal barrier integrity, enabling lipopolysaccharide (LPS) translocation that activates the TLR4/NF-B inflammatory axis (108)

The main possible mechanisms of the anti-liver fibrosis effects of caffeine are shown in Figure 2

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This imbalance can result in an excess of reactive oxygen species (ROS), which then overwhelms the bodys antioxidant defences, resulting in oxidative stress

Thirty mice were randomly allocated into five groups ( n = 6) as follows: Before the study, the mice were allowed to acclimatize for a week