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Phase 1 builds on the multimodal assessment tools discussed above including audiometry, standardized questionnaires, neuroimaging, electrophysiology, and circulating molecular markers to capture the multi-dimensional profile of an individual patient

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In adults over 55, prolonged-release melatonin improved sleep quality and morning alertness in a randomized trial of 354 people [6]

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Water solubility also has a direct impact on nutritional quality of food sources of vitamin B12

Both of these numbers come from the 1989 study that used rabbit ears