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Weight management in people with epilepsy is complex because some antiepileptic drugs promote weight gain, and rapid weight loss itself can occasionally trigger seizure changes
Visceral adipose tissue, the metabolically active fat surrounding internal organs, responds differently to cagrilintide than subcutaneous fat
J Clin Endocrinol Metab 108(4):920930 ElSayed NA, Aleppo G, Aroda VR, Bannuru RR, Brown FM, Bruemmer D et al (2023) 2 Classification and diagnosis of diabetes: standards of care in diabetes2023
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We start the medication at a very low dose to allow the body to adjust and then gradually increase it. This step-by-step approach helps patients tolerate the medication while promoting effective hunger control and weight loss
Phase Maintenance Weeks 25+ Retatrutide 12 mg/week Cagrilintide 2.4 mg/week Notes Full four-receptor coverage if tolerated
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